4^th World Conference on Vaccine and Immunology September 16-16, 2022 Osaka, Japan

TRACK 1: Novel Corona virus (COVID-19)

Corona viruses are positive sense single stranded RNA viruses that cause infection in nose, sinuses, or upper throat. It belongs to family of SARS and MERS. COVID-19 is the illness caused by SARS-COV-2, first outbreak occur Wuhan city in China.

TRACK 2: HPV and RV Vaccines

Human papillomavirus vaccine (HPV) vaccine is mostly given to children, adults and pregnant women. Researchers are working to develop therapeutic HPV vaccines, instead of preventing HPV infection it will also prevent cancer developing in women due to HPV. Rotavirus vaccines are in wide use universally, and have made an evident impact on the burden of disease.

• Adolescent health behaviours
• Sexually transmitted infections
• Abdomen pain
• Environmental enteropathy
• Circadian rhythm.         

TRACK 3: Vaccine Safety and efficacy  

Since last two centuries vaccines are known to provide a safe and effective means by preventing various infectious diseases. But safety of some vaccines are questioned in recent years, the currently available vaccines are million-fold safer than the diseases they are designed to prevent. However, vaccines should always be used along with public health interventions. One most important intervention is having proper knowledge about the vaccine as public might believe that vaccines are unsafe and not needed. Some vaccines are given via injection (intraveinous, subcutaneous, intramuscular and peritoneal) while others are given orally and intranasally. New vaccines are also investigated for topical and intravaginal use. In future safe and effective vaccines will be developed for preventing number of bacterial, viral, fungal and protozoan diseases.

TRACK 4: Vaccine Technology   

The Vaccine that are being used in the here and now primarily comprise of slaughtered immunizations, live attenuated vaccines or sub-unit immunizations. These sorts of Vaccine have demonstrated to be powerful especially in reducing the clinical indication following openness to destructive field strains of the pathogens. Nonetheless, just a set number of viral diseases can be forestalled by live constricted viral antibodies state and most DNA-containing viruses have the possibility to set up tenacious (or inert) contamination. New popular strains may emerge by recombination of the antibody infection with other viral strains in creature populaces; pregnant animals or their posterity might be antagonistically influenced by the immunization strain. Certain clearly a virulent viral strains can return to destructiveness, either by have instigated proteolysis or surface proteins of the phenotype, as in the actuation of the HN and F0 proteins of flu infection or by changes in the genotype, as in the inversion of weakened oral Sabin poliovirus Vaccine. 

TRACK 5: DNA Vaccines 

DNA vaccines are simple rings of DNA containing a gene encoding an antigen. DNA vaccination is an approach for protecting an animal against disease by injecting it with naturally engineered DNA so cells directly produce an antigen, resulting in a vigilant immunological response. DNA vaccines are considerably clean and cheaper to design and heat stability, flexible to genetic manipulation and mimic viral infection.

• Recombinant vaccines
• Next generation DNA vaccines
• Delivery methods
• Plasmid-based DNA vaccines
• DNA construct optimizationTRACK

Track 6: Immunogenetics  and immune tolerance 

Immunogenetics is the branch of immunology that deals with the study of genetic basis of immune response. It also deals with study of normal immunological pathways and identification of genetic variation that leads to immune defects, which further leads to identification of new therapeutic targets for immune diseases. Immune tolerance is a state of immune system where it unrespond to a substance or tissue that has the capacity to generate immune response in a organism.

TRACK 7: Immuno-informatics  

Immuno-informatics is the study of molecules of the immune system by using informatics techniques. It helps in efficient and effective predictions of immunogenicity. This is done at the level of epitopes, subunit vaccines, or weakend or inactive pathogens. Immunogenicity is the ability of the pathogen or a part or molecule of pathogen to induce specific immune response when first exposed to surveillance by the immune system.

TRACK 8: Inflammation and immuno therapies

Inflammation is a vital part of the immune system’s response to infection and injury. It is body’s way of signaling the immune system to heal and repair damaged tissue and also defend itself against foreign invaders like viruses, bacteria and fungi. Immunotherapy is the biological therapy that helps in treating disease either by activating or suppressing immune system.

Activation Immunotherapy

Supression Immunotherapy

TRACK 9: Immunology and its future research

Immunology is the field of biomedical science that deals with the structure and functions of immune system in all organisms. The immune system provides protection against infection through various lines of defence. If immune system is not functional it leads to several diseases like allergy, cancer and auto immune diseases. Immune system is basically categorised into two types: innate immunity and adaptive immunity. Adaptive immunity  further classified into humoral and cell mediated immunity.

TRACK 10: Immune regulation  

It is the regulatory adjustment of the immune system. It is nothing but a balance between activation and suppression of effector cell to achieve an efficient immune response without damaging the host organism. It can be 2 types.

Natural-Homeostasis, where immune system self regulates to adjust immune responses

Human induced forms-Immune responses are induced, amplified, attenuated and prevented according to therapeutic goals.

TRACK 11: Preclinical and Clinical Safety of DNA Vaccines 

DNA antibodies depend on the exchange of hereditary material, encoding an antigen, to the cells of the immunization beneficiary. Regardless of exclusive requirements of DNA antibodies because of promising preclinical information their clinical utility remaining parts dubious. Nonetheless, much information is accumulated in preclinical and clinical examinations about the wellbeing of DNA immunizations. Here we survey current information about the security of DNA antibodies. Wellbeing worries of DNA antibodies identify with hereditary, immunologic, poisonous, and ecological impacts. In this audit we give an outline of discoveries identified with the wellbeing of DNA antibodies, gotten up until now. We presume that the likely dangers of DNA antibodies are negligible. Nonetheless, their wellbeing issues may contrast one case at a time case, and they ought to be dealt with appropriately.

TRACK 12: Vaccine Bioprocess and Manufacturing     

Scientist have made breakthrough in bio-processing and analytical techniques to support vaccine development. These technologies have helped vaccine manufacturers achieve constant product purity, quality rapidly and inexpensive. Although interest in the development and manufactures of vaccines continues to grow due to the rapid growth of the global vaccine market, this area of the biotech industry is still remain challenging and complex.

TRACK 13: Vaccine research and development

Vaccine development is an activity which focuses on various technological initiatives and applied research that enhances and promotes improved systems and practices for safety of vaccines. Vaccine development is the long, complex and tedious process that last for 10-15 years, involving both private and public.