Anesthesiology and Immunology

The interactions of and operation with components of the may leave considerable importance for both patients and anesthetists. Additionally, chronic exposure to trace amounts of may alter immune defenses and possibly explain the reported increases in malignancies and surgical trauma may be associated with clinically important immunosuppression. A brief overview of basic immunology is presented followed by a more detailed account of the effects of anesthesia and surgery on immune competence. The immune system is a highly complex network of cells, organs, and tissues that protect our body from foreign intruders like bacteria, viruses or fungi. Early researchers demonstrated that isoflurane and sevoflurane (commonly used volatile anesthetics) can directly bind to and impair functions of a receptor (adhesion molecule) present on immune cells, called leukocyte function-associated antigen-1 (LFA-1).

  • Pre and Post Operation Care Sedation
  • Emergency Care
  • Pulmonology
  • Pain Medicine
  • Palliative Care

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